NEWS
29/01/2024
We've posted on ChemRxiv our findings on the organocatalytic hydration of activated alkynes using cysteine as the catalyst. A revised version will shortly be posted, incorporating theoretical insights into this fascinating reaction. We believe this study represents a significant step towards the development of sustainable and cost-effective alternatives to current strategies in alkyne hydration. Thanks to all involved!
https://chemrxiv.org/engage/chemrxiv/article-details/65aa1c5f9138d2316143514a
19/07/2023
Honoured and humbled to receive the Spanish Biotechnology Society 2023 Young Researchers Prize. Off to Madrid to attend to the Spanish Biotechnology Society (SEBiot) conference. Thanks SEBiot for this wonderful recognition and Solmeglas for the sponsorship.
24/06/2023
Off to BIOTRANS 2023 in beautiful La Rochelle with my colleagues from the University of Oviedo. Can't wait to discuss science and see my friends from the Turner Lab!
15/02/2023
Thrilled to see our chemoenzymatic process for the synthesis of enantioenriched C(1)-allylated tetrahydroisoquinolines published in the Journal of the American Chemical Society. Congrats to everyone involved, especially Jack for the hard work. https://pubs.acs.org/doi/10.1021/jacs.2c09176
20/01/2023
We have published a Synpacts article describing our recent work on the synthesis of chiral 1,4-nitro alcohols in the context of chemoenzymatic cascades ft organo- and biocatalysts. Many thanks Synlett for the invitation and the opportunity to highlight our research!https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0042-1751403
03/01/2023
Proud and happy to be amongst the 2023 Thieme Chemistry Journal award winners!Thanks for this recognition and congrats to the other awardees.
01/01/2023
The new year has come with some changes. We are now based at the University of Oviedo. We will continue our work on the construction of novel cascades involving chemo- and enzyme catalysis as well as on the discovery of new enzymes thanks to the funding received from the Agencia Estatal de Investigación PID2020-113351RA-100/AEI/10.13039/501100011033 and TED2021-130803B-I00 MCIN/AEI /10.13039/501100011033 NextGenerationEU/PRTR
17/12/2022
Our proposal on the discovery of novel oxidative biocatalysts in collaboration with Dr. Patricia Ferreira from the University of Zaragoza has been funded! Many thanks to the Agencia Estatal de Investigación. Project reference: TED2021-130803B-I00 MCIN/AEI /10.13039/501100011033 NextGenerationEU/PRTR
24/11/2022
Honoured to receive the 2022 Chemistry Prize from the Royal Academy of Sciences of Zaragoza. Many thanks to ARAID, the gruoups of Raquel P. Herrera and Conchita Gimeno and all my coworkers for their support.
07/09/2022
Our work on the stereoselective synthesis of chiral nitro alcohols through a chemoenzymatic cascade combining organo- and biocatalysts is now available "open access" in Angewandte Chemie. Thanks and congrats to Christian and Raquel!https://onlinelibrary.wiley.com/doi/10.1002/anie.202209159
27/06/2022
New preprint alert! We have posted our work on the stereoselective synthesis of chiral nitro alcohols from aldehydes via a three-step one-pot sequential cascade combining organo- and biocatalysts. A simple and effective way to build synthetic complexity under mild reaction conditions.https://chemrxiv.org/engage/chemrxiv/article-details/62a9ba2ae00d4e12cd2b576b
13/06/2022
The final version of our review is now available. Here we examine recent examples in the construction of chemoenzymatic cascades, current strategies to overcome limitations and discuss future challenges in the field.https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/ejoc.202200093
07/06/2022
Sergio Paricio has been awarded the Santander Prize in digital competence for his presentation about the project he developed in our lab for his final year dissertation. Congrats!Links below:https://catbs.unizar.es/articulos/premios-santander-a-competencias-digitales-en-trabajos-fin-de-estudios-de-la-universidad-de-zaragoza-2Youtube: https://youtu.be/UoBEsNJnV-I
23/05/2022
Our open-access review on chemoenzymatic cascades is under the "accepted articles" section of the European Journal of Organic Chemistry. We are happy to be part of the #NextGenOrgChem special collection and congrats to Christian for his first contribution as the 1st author! https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/ejoc.202200093
26/11/2021
Very excited to share our review on the enzymatic formation of C-N, C-C and C-O bonds involving different enzyme families. You can find it now in ChemBioChem as part of a #NextGenBiocat issue in collaboration with the Turner Lab.https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cbic.202100464
25/10/2021
Happy to receive the 2021 Chemistry Biology Interface Division Horizon Prize: Rita and John Cornforth Award. For the development of new biocatalysts for asymmetric reductive amination, from fundamental understanding of mechanism and structure to applications on an industrial scale.
11/08/2021
Our book chapter in collaboration with Dr. Sebastian Cosgrove and Prof. Nicholas Turner on the directed evolution of biocatalysts for the production of APIs is finally onlinehttps://onlinelibrary.wiley.com/doi/10.1002/9783527815128.ch11
19/06/2021
Our proposal on the construction of new chemoenzymatic cascades has been granted and will be funded by the "Agencia Estatal de Investigación" from September 2021 for 3 years. (PID2020-113351RA-100/AEI/ 10.13039/501100011033 COOPCAT project)